GSK-4716

GSK-4716 is a selective ERRβ/γ agonist.

Product Specifications

CAS Number

[101574-65-6]

UNSPSC

12352005

Hazard Statement

H317, H400, H410

Target

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/GSK-4716.html

Purity

99.63

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N/N=C/C1=CC=C(C(C)C)C=C1)C2=CC=C(O)C=C2

Molecular Formula

C17H18N2O2

Molecular Weight

282.34

Precautions

H317, H400, H410

References & Citations

[1]Wang SC, et al. An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells. Mol Cell Endocrinol. 2010 Feb 5;315 (1-2) :146-52.|[2]Rangwala SM, et al. Estrogen-related receptor gamma is a key regulator of muscle mitochondrial activity and oxidative capacity. J Biol Chem. 2010 Jul 16;285 (29) :22619-29.