DAPT (Highly Pure)

<strong>DAPT (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2014895_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 432.47_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8oC_x000D_ <strong>Keywords:</strong> (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu, (3,5-Difluorophenylacetyl)-L-alanyl-L-2-phenylglycine tert-Butyl Ester, tert-Butyl (S)-2-[(S)-2-[2-(3,5-Difluorophenyl)acetamido]propanamido]-2-phenylacetate_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Sharma R, Kumar P, Prashanth SP, Belagali Y. Dual Antiplatelet Therapy in Coronary Artery Disease Cardiol Ther. 2020 Dec;9(2):349-361._x000D_ 2: Toyota T, Shiomi H, Morimoto T, Natsuaki M, Kimura T. Short versus prolonged dual antiplatelet therapy (DAPT) duration after coronary stent implantation: A comparison between the DAPT study and 9 other trials evaluating DAPT duration PLoS One. 2017 Sep 20;12(9):e0174502._x000D_ 3: Capodanno D, Alfonso F, Levine GN, Valgimigli M, Angiolillo DJ. ACC/AHA Versus ESC Guidelines on Dual Antiplatelet Therapy: JACC Guideline Comparison J Am Coll Cardiol. 2018 Dec 11;72(23 Pt A):2915-2931._x000D_ 4: Banerjee S, Angiolillo DJ, Boden WE, Murphy JG, Khalili H, Hasan AA, Harrington RA, Rao SV. Use of Antiplatelet Therapy/DAPT for Post-PCI Patients Undergoing Noncardiac Surgery J Am Coll Cardiol. 2017 Apr 11;69(14):1861-1870._x000D_ 5: Yang JY, Shen DY, Wang J, Dai JF, Qin XY, Hu Y, Lan R. DAPT Attenuates Cadmium-Induced Toxicity in Mice by Inhibiting Inflammation and the Notch/HES-1 Signaling Axis Front Pharmacol. 2022 Apr 29;13:902796._x000D_ 6: Aguayo-Ortiz R, Guzmán-Ocampo DC, Dominguez L. Toward the Characterization of DAPT Interactions with γ-Secretase ChemMedChem. 2019 May 17;14(10):1005-1010._x000D_ 7: Calcagno S, Lucisano L, Mancone M, Cavallo E, Pennacchi M, Stio RE, Sardella G. Bleeding versus thrombosis: role of short DAPT in complex lesions Minerva Cardioangiol. 2015 Dec;63(6):533-46. Epub 2015 Sep 2._x000D_ 8: Wei X, Fan B, Chen X, Cheng Y, Zhang A, Yu S, Zhang S, Zhao H. DAPT inhibits titanium particle-induced osteolysis by suppressing the RANKL/Notch2 signaling pathway J Biomed Mater Res A. 2020 Nov 1;108(11):2150-2161._x000D_ 9: Sharp MK, Haneef R, Ravaud P, Boutron I. Dissemination of 2014 dual antiplatelet therapy (DAPT) trial results: a systematic review of scholarly and media attention over 7 months BMJ Open. 2017 Nov 3;7(11):e014503._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31237644">10: Watanabe H, Domei T, Morimoto T, Natsuaki M, Shiomi H, Toyota T, Ohya M, Suwa S, Takagi K, Nanasato M, Hata Y, Yagi M, Suematsu N, Yokomatsu T, Takamisawa I, Doi M, Noda T, Okayama H, Seino Y, Tada T, Sakamoto H, Hibi K, Abe M, Kawai K, Nakao K, Ando K, Tanabe K, Ikari Y, Hanaoka KI, Morino Y, Kozuma K, Kadota K, Furukawa Y, Nakagawa Y, Kimura T; STOPDAPT-2 Investigators. Effect of 1-Month Dual Antiplatelet Therapy Followed by Clopidogrel vs 12-Month Dual Antiplatelet Therapy on Cardiovascular and Bleeding Events in Patients Receiving PCI: The STOPDAPT-2 Randomized Clinical Trial JAMA. 2019 Jun 25;321(24):2414-2427. </a>_x000D_ _x000D_ <strong>Products Related to DAPT (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>