Phospho-CDK1 (T161) Recombinant Rabbit Monoclonal Antibody [PSH03-42]

Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase, and is a key player in cell cycle regulation. It has been highly studied in the budding yeast S. cerevisiae, and the fission yeast S. pombe, where it is encoded by genes cdc28 and cdc2, respectively. With its cyclin partners, Cdk1 forms complexes that phosphorylate a variety of target substrates (over 75 have been identified in budding yeast); phosphorylation of these proteins leads to cell cycle progression.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Cdc 2 antibody Cdc2 antibody CDC28A antibody CDK 1 antibody CDK1 antibody CDK1_HUMAN antibody CDKN1 antibody CELL CYCLE CONTROLLER CDC2 antibody Cell division control protein 2 antibody Cell division control protein 2 homolog antibody Cell division cycle 2 G1 to S and G2 to M antibody Cell division protein kinase 1 antibody Cell Divsion Cycle 2 Protein antibody Cyclin Dependent Kinase 1 antibody Cyclin-dependent kinase 1 antibody DKFZp686L20222 antibody MGC111195 antibody p34 Cdk1 antibody p34 protein kinase antibody P34CDC2 antibody

Abbreviation

CDK1, CDC2, CDC28A, CDKN1, P34CDC2

Swiss Prot

P06493 Human, P11440 Mouse, P39951 Rat

Cellular Locus

Nucleus, Mitochondrion, Cytoplasm, cytoskeleton, microtubule organizing center, spindle.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding Thr161 of CDK1.

Isotype

IgG

Clone

PSH03-42

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

HeLa cell lysate, HeLa treated with 100nM Calyculin A for 30 minutes cell lysate, Jurkat cell lysate, Jurkat treated with 100nM Calyculin A for 30 minutes cell lysate, NIH/3T3 cell lysate, NIH/3T3 treated with 100nM Calyculin A for 30 minutes cell lysate, PC-12 cell lysate, PC-12 treated with UV for 1 hour cell lysate, human cervix cancer tissue, Jurkat cells treated with 100nM Calyculin A for 30 minutes, HeLa cells treated with 100nM Calyculin A for 30 minutes, NIH/3T3 cells treated with 100nM Calyculin A for 30 minutes.