Carbohydrate Antigen 15-3 (CA15-3) Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

[CA15-3]

Storage Conditions

Short-term store at 2-8 °C. Long term store at-20 °C. Avoid multiple freeze/thaw cycles

Specificity

Specific for the tandem repeat of the MUC-1 core. Recognizes the hexapeptide (TRPAPG). The MUC-1 mucin (Cancer Antigen CA15-3) is secreted from tumor cells. The apo-protein of the MUC-1 mucin contains a transmembrane domain, a cytoplasmic domain, and an extracellular carbohydrate rich domain. The extracellular domain is characterized by polymorphism with respect to the number of a 20 amino acid tandem repeat (VNTR polymorphism).