IDE-IN-2

IDE-IN-2 (Compound 4) is an inhibitor for insulin-degrading enzyme. IDE-IN-2 is predicted to have CYP3A4, CYP2C19, hERG, NADP+, HIF1α and histidine kinase inhibitory activities, and has potential biological activity in anti-diabetic, anti-tumor, anti-bacterial aspects, according to the in silico prediction[1].

Product Specifications

CAS Number

[49619-58-1]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

IDE; Proteolytic Enzyme

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ide-in-2.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)C1=CC2=C(C=C1)OC=C(C=O)C2=O

Molecular Formula

C13H12O3

Molecular Weight

216.23

Precautions

H315, H319, H335

References & Citations

[1]Saif MZ, et al., Investigating the potential of 6-substituted 3-formyl chromone derivatives as anti-diabetic agents using in silico methods. Sci Rep. 2024 Jun 8;14 (1) :13221.