Recombinant Human MAP4K3/GLK Protein (GST Tag, Active)

<strong>Recombinant Human MAP4K3/GLK Protein (GST Tag, Active)</strong>_x000D_ <strong>Catalog number:</strong> B2018999_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~70 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −80°C_x000D_ <strong>Keywords:</strong> GLK Protein, Human; MAPKKKK3 Protein, Human; MEKKK 3 Protein, Human; MEKKK3 Protein, Human; RAB8IPL1 Protein, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yan L, Mieulet V, Burgess D, Findlay GM, Sully K, Procter J, Goris J, Janssens V, Morrice NA, Lamb RF. PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR Mol Cell. 2010 Mar 12;37(5):633-42._x000D_ 2: Findlay GM, Yan L, Procter J, Mieulet V, Lamb RF. A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling Biochem J. 2007 Apr 1;403(1):13-20._x000D_ 3: Song Y, Zhang F, Li L, Song B, Xu J, Wang G, Zheng Z. MiR-338-3p inhibits growth of glioblastoma through targeting MAP4K3 Minerva Med. 2021 Aug;112(4):531-533._x000D_ 4: Schriever SC, Deutsch MJ, Adamski J, Roscher AA, Ensenauer R. Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism J Nutr Biochem. 2013 May;24(5):824-31._x000D_ 5: Goljanek-Whysall K, Pais H, Rathjen T, Sweetman D, Dalmay T, Münsterberg A. Regulation of multiple target genes by miR-1 and miR-206 is pivotal for C2C12 myoblast differentiation J Cell Sci. 2012 Aug 1;125(Pt 15):3590-600._x000D_ 6: Ramjaun AR, Angers A, Legendre-Guillemin V, Tong XK, McPherson PS. Endophilin regulates JNK activation through its interaction with the germinal center kinase-like kinase J Biol Chem. 2001 Aug 3;276(31):28913-9._x000D_ 7: Chuang HC, Hsueh CH, Hsu PM, Huang RH, Tsai CY, Chung NH, Chow YH, Tan TH. SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19 EMBO Mol Med. 2022 Sep 7;14(9):e15904._x000D_ 8: Chuang HC, Tan TH. MAP4K Family Kinases and DUSP Family Phosphatases in T-Cell Signaling and Systemic Lupus Erythematosus Cells. 2019 Nov 13;8(11):1433._x000D_ 9: Wang CW, Chuang HC, Tan TH. ACE2 in chronic disease and COVID-19: gene regulation and post-translational modification J Biomed Sci. 2023 Aug 22;30(1):71._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31640697">10: Chuang HC, Tan TH. MAP4K3/GLK in autoimmune disease, cancer and aging J Biomed Sci. 2019 Oct 22;26(1):82. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human MAP4K3/GLK Protein (GST Tag, Active) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>