Macarangin
Macarangin can be isolated from propolis. Macarangin has DPPH radical-scavenging activity and shows anti-inflammatory activities via inhibiting the activation process of NLRP3 inflammasome[1][2].
Product Specifications
CAS Number
129385-65-5
UNSPSC
12352005
Target
NOD-like Receptor (NLR) ; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/macarangin.html
Smiles
OC1=C(C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)/CC/C=C(C)/C)C(O)=C3C1=O
Molecular Formula
C25H26O6
Molecular Weight
422.47
References & Citations
[1]Petrova A, et al. New biologically active compounds from Kenyan propolis. Fitoterapia. 2010;81 (6) :509-514. |[2]Hu Y, et al. Total synthesis/semi-synthesis of natural isopentenyl flavonoids with inhibitory activity on NLRP3 inflammasome. Bioorg Med Chem Lett. 2024;107:129777.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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