Macarangin
Macarangin can be isolated from propolis. Macarangin has DPPH radical-scavenging activity and shows anti-inflammatory activities via inhibiting the activation process of NLRP3 inflammasome[1][2].
Product Specifications
CAS Number
129385-65-5
UNSPSC
12352005
Target
NOD-like Receptor (NLR) ; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/macarangin.html
Smiles
OC1=C(C2=CC=C(O)C=C2)OC3=CC(O)=C(C/C=C(C)/CC/C=C(C)/C)C(O)=C3C1=O
Molecular Formula
C25H26O6
Molecular Weight
422.47
References & Citations
[1]Petrova A, et al. New biologically active compounds from Kenyan propolis. Fitoterapia. 2010;81 (6) :509-514. |[2]Hu Y, et al. Total synthesis/semi-synthesis of natural isopentenyl flavonoids with inhibitory activity on NLRP3 inflammasome. Bioorg Med Chem Lett. 2024;107:129777.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC472564-500 1x 500 µL
DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/2564R), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
![MALT1 Mouse Monoclonal Antibody [Clone ID: OTI4H10]](https://cdn.genprice.uk/products/937/68dd18b9061270361e908065/imageurl/cf807327.webp)
CF807327 100 µg
MALT1 Mouse Monoclonal Antibody [Clone ID: OTI4H10]
Sign In for Pricing
View Details 
![PerCP/Cyanine5.5 Anti-Mouse CD4 Antibody[GK1.5]](https://cdn.genprice.uk/products/763/68dd149f061270361e7d053b/imageurl/e-ab-f1097j.webp)
E-AB-F1097J-01 50 Tests
PerCP/Cyanine5.5 Anti-Mouse CD4 Antibody[GK1.5]
Sign In for Pricing
View Details