Dimethyl-F-OICR-9429-COOH
Dimethyl-F-OICR-9429-COOH a ligand for WD40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1 intermediate 19. Dimethyl-F-OICR-9429-COOH can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2407458-49-3]
UNSPSC
12352005
Hazard Statement
H301, H311, H331
Target
Ligands for Target Protein for PROTAC; WDR5
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dimethyl-f-oicr-9429-cooh.html
Concentration
10mM
Purity
98.11
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(C(C(C(F)(F)F)=C1)=CNC1=O)NC2=C(N3C[C@@H](N([C@@H](C3)C)C)C)C=CC(C4=CC(C(O)=O)=CC=C4F)=C2
Molecular Formula
C27H26F4N4O4
Molecular Weight
546.51
Precautions
H301, H311, H331
References & Citations
[1]Jin J, et, al. Wd40 repeat domain protein 5 (wdr5) degradation/disruption compounds and methods of use. WO2019246570A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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