SC66

SC66 is an Akt inhibitor, reduces cell viability in a dose- and time-dependent manner, inhibits colony formation and induces apoptosis in hepatocellular carcinoma (HCC) cells.

Product Specifications

CAS Number

[871361-88-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Akt; Apoptosis

Type

Reference compound

Related Pathways

Apoptosis; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/SC66.html

Purity

99.65

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1/C(CCC/C1=C\C2=CC=NC=C2)=C/C3=CC=NC=C3

Molecular Formula

C18H16N2O

Molecular Weight

276.33

Precautions

H302, H315, H319, H335

References & Citations

[1]Cusimano A, et al. Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells. Oncotarget. 2015 Jan 30;6 (3) :1707-22.