Topoisomerase II inhibitor 14
Selected Variant
HY-W278582-01
Size: 5 mg
Topoisomerase II inhibitor 14 is a potent topoisomerase II inhibtor. Topoisomerase II inhibitor 14 induces apoptosis and arrests cell cycle at S phase and G2-M phases. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO. Topoisomerase II inhibitor 14 can be used for the study of neck squamous cell carcinoma (HNSCC) [1].
Product Specifications
CAS Number
305343-00-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Topoisomerase
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-ii-inhibitor-14.html
Purity
99.68
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=NC(C2=CC=C(Cl)C=C2Cl)N3C4=CC=CC=C4N=C3N1
Molecular Formula
C15H11Cl2N5
Molecular Weight
332.19
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Cytokeratin 10 (Suprabasal Epithelial Marker) (rKRT10/1275), CF647 conjugate, 0.1mg/mL
PAX8 (Renal Cell Marker) (PAX8/1491), CF405S conjugate, 0.1mg/mL
CD31 / PECAM-1 (Endothelial Cell Marker) (C31/2876R), CF640R conjugate, 0.1mg/mL
TRAcP (Tartrate-Resistant Acid Phosphatase) (Hairy Cell Leukemia Marker) (rACP5/1070), CF647 conjugate, 0.1mg/mL
SUMO-1 (SM1/495), CF568 conjugate, 0.1mg/mL
