Cyfra21-1 (CK19) Antibody

Ks 19.1 represents an excellent marker to discriminate glandular epithelial carcinomafrom those of different origin. No reaction with hepatocellular carcinoma.Polypeptide reacting: Mr 40 000 polypeptide (keratin K19; formerly also designatedcytokeratin 19) of human glandular epithelia. The epitope has been localized on aa.311-335 (QSQLSMKAALEDTLAETEARFGAQLA) of the alpha-helical fragment.Tumors specifically detected: All tested adenocarcinoma; cholangio ca. of liver; renal cell carcinoma; transitional cell ca. of the bladder; ovary ca.; squamous cell ca. of cervix, bronchus and lung (intermediate type); mesothelioma; carcinoid tumor of bronchus; breast ca.; thymoma.