BChE-IN-31
BChE-IN-31 (Compound 14d) is a selective BChE inhibitor with an IC50 of 65 nM. BChE-IN-31 inhibits the self-induced aggregation of neurotoxic amyloid-β (Aβ) peptide[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bche-in-31.html
Solubility
10 mM in DMSO
Smiles
O=C1NCCCC2=C1C3=CC=CC=C3N2CCCCCCCN4CCN(CCC5=CC=CC=C5)CC4
Molecular Formula
C31H42N4O
Molecular Weight
486.69
References & Citations
[1]Samarelli F, et al., Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino [4, 3-b] indol-1 (2H) -one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults[J]. European Journal of Medicinal Chemistry, 2024: 116353.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Frequently Asked Questions
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