Hepcidin 1 (Mouse)

<strong>Hepcidin 1 (Mouse)</strong> <strong>Catalog number:</strong> MDP0795 <strong>CAS Number: </strong>277302-47-3 <strong>Sequence: </strong>Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr (Disulfide bonds undetermined) <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 2754 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization Science. 2004 Dec 17;306(5704):2090-3. 2: Schwartz AJ, Das NK, Ramakrishnan SK, Jain C, Jurkovic MT, Wu J, Nemeth E, Lakhal-Littleton S, Colacino JA, Shah YM. Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload J Clin Invest. 2019 Jan 2;129(1):336-348. 3: Yazdani Y, Keyhanvar N, Kalhor HR, Rezaei A. Functional analyses of recombinant mouse hepcidin-1 in cell culture and animal model Biotechnol Lett. 2013 Aug;35(8):1191-7. 4: Zhao GY, Di DH, Wang B, Huang X, Xu YJ. Effects of mouse hepcidin 1 treatment on osteoclast differentiation and intracellular iron concentration Inflammation. 2015 Apr;38(2):718-27. 5: Tjalsma H, Laarakkers CM, van Swelm RP, Theurl M, Theurl I, Kemna EH, van der Burgt YE, Venselaar H, Dutilh BE, Russel FG, Weiss G, Masereeuw R, Fleming RE, Swinkels DW. Mass spectrometry analysis of hepcidin peptides in experimental mouse models PLoS One. 2011 Mar 8;6(3):e16762. 6: Ilyin G, Courselaud B, Troadec MB, Pigeon C, Alizadeh M, Leroyer P, Brissot P, Loréal O. Comparative analysis of mouse hepcidin 1 and 2 genes: evidence for different patterns of expression and co-inducibility during iron overload FEBS Lett. 2003 May 8;542(1-3):22-6. 7: Chung B, Chaston T, Marks J, Srai SK, Sharp PA. Hepcidin decreases iron transporter expression in vivo in mouse duodenum and spleen and in vitro in THP-1 macrophages and intestinal Caco-2 cells J Nutr. 2009 Aug;139(8):1457-62. 8: Nemere I, Hintze K. Novel hormone "receptors" J Cell Biochem. 2008 Feb 1;103(2):401-7. 9: Probst S, Fels J, Scharner B, Wolff NA, Roussa E, van Swelm RPL, Lee WK, Thévenod F. Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium Arch Toxicol. 2021 Aug;95(8):2719-2735. <a href="https://pubmed.ncbi.nlm.nih.gov/15684062">10: Lee P, Peng H, Gelbart T, Wang L, Beutler E. Regulation of hepcidin transcription by interleukin-1 and interleukin-6 Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1906-10. </a> <br><strong>Products Related to Hepcidin 1 (Mouse) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>