Fibroblast Growth Factor-6 (Human)

<strong>Human Fibroblast Growth Factor-6</strong>_x000D_ <strong>Catalog number:</strong> B2010360_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Human Fibroblast Growth Factor-6 expressed in E. coli. This protein acts as a potent mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuFGF-6; HBGF-6; HST-2; HSTF-2_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Othman A, Mubarak R, Sabry D. Fibroblast growth factor-6 enhances <i>CDK2</i>_x000D_ and <i>MATK</i> expression in microvesicles derived from human stem cells_x000D_ extracted from exfoliated deciduous teeth. F1000Res. 2018 May 22;7:622._x000D_ _x000D_ 2: Shamsi F, Xue R, Huang TL, Lundh M, Liu Y, Leiria LO, Lynes MD, Kempf E, Wang_x000D_ CH, Sugimoto S, Nigro P, Landgraf K, Schulz T, Li Y, Emanuelli B, Kothakota S,_x000D_ Williams LT, Jessen N, Pedersen SB, Böttcher Y, Blüher M, Körner A, Goodyear LJ,_x000D_ Mohammadi M, Kahn CR, Tseng YH. FGF6 and FGF9 regulate UCP1 expression_x000D_ independent of brown adipogenesis. Nat Commun. 2020 Mar 17;11(1):1421._x000D_ _x000D_ 3: Xu Y, Tan Q, Hu P, Yao J. Characterization and expression analysis of FGF6_x000D_ (fibroblast growth factor 6) genes of grass carp (Ctenopharyngodon idellus)_x000D_ reveal their regulation on muscle growth. Fish Physiol Biochem. 2019_x000D_ Oct;45(5):1649-1662._x000D_ _x000D_ 4: Coulier F, Pizette S, Ollendorff V, deLapeyrière O, Birnbaum D. The human and_x000D_ mouse fibroblast growth factor 6 (FGF6) genes and their products: possible_x000D_ implication in muscle development. Prog Growth Factor Res. 1994;5(1):1-14._x000D_ _x000D_ 5: Rescan PY. Identification of a fibroblast growth factor 6 (FGF6) gene in a_x000D_ non-mammalian vertebrate: continuous expression of FGF6 accompanies muscle fiber_x000D_ hyperplasia. Biochim Biophys Acta. 1998 Dec 22;1443(3):305-14._x000D_ _x000D_ 6: Ropiquet F, Giri D, Kwabi-Addo B, Mansukhani A, Ittmann M. Increased_x000D_ expression of fibroblast growth factor 6 in human prostatic intraepithelial_x000D_ neoplasia and prostate cancer. Cancer Res. 2000 Aug 1;60(15):4245-50. PMID:_x000D_ 10945637._x000D_ _x000D_ 7: Batoz M, Coll Fresno PM, Pizette S, Raffioni S, Birnbaum D, Coulier F. A_x000D_ diphtheria toxin/fibroblast growth factor 6 mitotoxin selectively kills_x000D_ fibroblast growth factor receptor-expressing cell lines. Cell Growth Differ._x000D_ 1995 Sep;6(9):1143-9. PMID: 8519691._x000D_ _x000D_ 8: Xu Z, Ramachandran S, Gunasekaran M, Zhou F, Trulock E, Kreisel D, Hachem R,_x000D_ Mohanakumar T. MicroRNA-144 dysregulates the transforming growth factor-β_x000D_ signaling cascade and contributes to the development of bronchiolitis obliterans_x000D_ syndrome after human lung transplantation. J Heart Lung Transplant. 2015_x000D_ Sep;34(9):1154-62._x000D_ _x000D_ 9: Pessina A, Gagliardi G, Croera C, Foti P, Dassi C, Brambilla P, Neri MG._x000D_ Secretion of basic fibroblast growth factor (FGF-2) by WEHI-3B myelomonocytic_x000D_ leukemia cells. Growth Factors. 2002 Sep;20(3):121-9._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/16875743/">10: Armand AS, Laziz I, Chanoine C. FGF6 in myogenesis. Biochim Biophys Acta._x000D_ 2006 Aug;1763(8):773-8. </a>_x000D_ _x000D_ <strong>Products Related to Human Fibroblast Growth Factor-6 </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>