Thalidomide-piperidine-C-Pip-C2-Pip-C2-OH
Thalidomide-piperidine-C-Pip-C2-Pip-C2-OH (Compound C6) is a conjugate of the linker and E3 ligase ligand, that can be used in synthesis of PROTAC PARP1 degrader-30.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates; PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thalidomide-piperidine-c-pip-c2-pip-c2-oh.html
Smiles
OCCC1CCN(CCC2CCN(CC3CCN(C4=CC5=C(C(N(C6CCC(NC6=O)=O)C5=O)=O)C=C4)CC3)CC2)CC1
Molecular Formula
C33H47N5O5
Molecular Weight
593.76
References & Citations
[1]Wu M, et al., Discovery of a potent PARP1 PROTAC as a chemosensitizer for the treatment of colorectal cancer. Eur J Med Chem. 2025 Jan 15;282:117062.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC740257-100 1x 100 µL
Cytokeratin, HMW (AE-3), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471081-500 1x 500 µL
CD45RO (190-2F2.5), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680679-100 1x 100 µL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040158-500 1x 500 µL
Cytokeratin 17 (E3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 