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ASN06917370

Product Specifications

UNSPSC Description

ASN06917370 is a former orphan receptor GPR17 ligand for the study of neurodegenerative diseases. ASN06917370 has an EC50 of 268 pM in [35S]GTPyS experiments[1].

Target Antigen

ROR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/asn06917370.html

Purity

99.23

Solubility

DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C(N1CCC(C2=NC3=C(N=NN3CC4=CC=CC=C4Cl)C(N2)=O)CC1)NC5=CC=C(C(F)(F)F)C=C5

Molecular Weight

531.92

References & Citations

[1]Eberini I, et al. In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases. J Comput Aided Mol Des. 2011 Aug;25(8):743-52.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-111323/ASN06917370-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-111323/ASN06917370-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

837404-68-9

Available Sizes

Curated Selection

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