ASN06917370
Product Specifications
UNSPSC Description
ASN06917370 is a former orphan receptor GPR17 ligand for the study of neurodegenerative diseases. ASN06917370 has an EC50 of 268 pM in [35S]GTPyS experiments[1].
Target Antigen
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/asn06917370.html
Purity
99.23
Solubility
DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(N1CCC(C2=NC3=C(N=NN3CC4=CC=CC=C4Cl)C(N2)=O)CC1)NC5=CC=C(C(F)(F)F)C=C5
Molecular Weight
531.92
References & Citations
[1]Eberini I, et al. In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases. J Comput Aided Mol Des. 2011 Aug;25(8):743-52.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111323/ASN06917370-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111323/ASN06917370-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
837404-68-9
Available Sizes
Curated Selection
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