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MMP-2 Rabbit Polyclonal Antibody

MMP-2 Rabbit Polyclonal Antibody

Product Specifications

Product Name Alternative

CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1; MMP2_HUMAN; MMP2; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2 (MMP-2) ; 3.4.24.24; matrix metallopeptidase 2; matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

UniProt

P08253

Reactivity

Human

Immunogen

KLH conjugated synthetic peptide derived from human MMP-2 (401-500/662aa)

Target

MMP2

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Cardiovascular Research; Musculoskeletal & Connective Tissue Research

Purification

Affinity purified by Protein A

Concentration

1mg/ml

Dilution

WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, Flow-Cyt=1μg/Test

Form

Liquid

Molecular Weight

62 kDa

References & Citations

Sahin Sultana, Rajen Dey, Biswadev Bishayi Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking Immunologic Research, 66, 97 (2018), Ayantika Kundu, Pratiti Ghosh, Biswadev Bishayi Vitexin along with verapamil downregulates efflux pump P-glycoprotein in macrophages and potentiate M1 to M2 switching via TLR4-NF-κB-TNFR5 pathway in Lipopolysaccharide treated mice Immunobiology, 229 (1), 152767 (2024), Berta H Ganizada 1 2 3, Koen D Reesink 3 4, Shaiv Parikh 3 4, Pepijn J M H Saraber 2 3 4, Jack P Cleutjens 3 5, Austin Isabella 2 3, Mathilde Q E Krebbekx 1 3, Armand M Jaminon 2 3, Cecile F M Maassen 2 3, Mitch J F G Ramaekers 3 6 7, Bart Spronck 3 4, Koen van der Laan 3 4, Rory R Koenen 2 3, Roberto Lorusso 1 3, Jos G Maessen 1 3, Elham Bidar 1 3, Leon J Schurgers Loss of wall stress homoeostasis in ascending thoracic aortic aneurysm: histomorphometric insights into patient variants J Physiol ., (2025)

Pubmed id

29218573, 38103391, 40581980

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Prediction Reactivity

Bovine, Equine, Mouse, Porcine, Rabbit, Rat, Sheep

Tested Applications

FC, ICC, IF, IHC-Fr, IHC-P, WB

Host or Source

Rabbit

Preservative

0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.

Isotype

IgG

Available Sizes

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