Glycohyocholic acid

Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Cholic acid (HY-N0324) and Glycine (HY-Y0966) . Glycohyocholic acid can be used in the study of hepatitis C-related cirrhosis and diabetes mellitus[1][2][3].

Product Specifications

CAS Number

[32747-08-3]

Product Name Alternative

GHCA

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glycohyocholic-acid.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@@H]1CC[C@]2([C@@]([H])(C1)[C@H]([C@H]([C@@]3([C@@]2(CC[C@]4([C@]3(CC[C@@]4([C@@H](CCC(NCC(O)=O)=O)C)[H])[H])C)[H])[H])O)O)C

Molecular Formula

C26H43NO6

Molecular Weight

465.62

References & Citations

[1]Guo L, et al. Plasma metabolomic profiles enhance precision medicine for volunteers of normal health. Proc Natl Acad Sci U S A. 2015 Sep 1;112 (35) :E4901-10.|[2]Yu H, et al. Chenodeoxycholic Acid as a Potential Prognostic Marker for Roux-en-Y Gastric Bypass in Chinese Obese Patients. J Clin Endocrinol Metab. 2015 Nov;100 (11) :4222-30. |[3]Fitian AI, et al. Integrated metabolomic profiling of hepatocellular carcinoma in hepatitis C cirrhosis through GC/MS and UPLC/MS-MS. Liver Int. 2014 Oct;34 (9) :1428-44.