Licarin A
Licarin A ((+) -Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA) -stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression[1].
Product Specifications
CAS Number
51020-86-1
Product Name Alternative
(+) -Licarin A
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX; Prostaglandin Receptor; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; GPCR/G Protein; Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/licarin-a-1.html
Purity
99.83
Solubility
DMSO : ≥ 50 mg/mL|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC1=CC=C([C@@H]2OC3=C(OC)C=C(/C=C/C)C=C3[C@H]2C)C=C1OC
Molecular Formula
C20H22O4
Molecular Weight
326.39
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
DP
Available Sizes
Frequently Asked Questions
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