Goitrin
Goitrin ((S) -Goitrin), a product of glucosinolate-myrosinase reactions, is a potent inhibitor of thyroid peroxidase. Goitrin can inhibit iodine utilization by the thyroid. Goitrin also exhibits anti-influenza virus (H1N1) activity[1][2][3].
Product Specifications
CAS Number
500-12-9
Product Name Alternative
(S) -Goitrin; L-5-Vinyl-2-thiooxazolidone
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Influenza Virus
Type
Natural Products
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/goitrin.html
Purity
99.66
Solubility
10 mM in DMSO
Smiles
S=C1O[C@@H](C=C)CN1
Molecular Formula
C5H7NOS
Molecular Weight
129.18
Precautions
H302, H315, H319
References & Citations
[1]Felker P, et, al. Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism. Nutr Rev. 2016 Apr;74 (4) :248-58.|[2]Wooding S, et, al. Genetics and bitter taste responses to goitrin, a plant toxin found in vegetables. Chem Senses. 2010 Oct;35 (8) :685-92.|[3]Nie LX, et, al. Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action. J Ethnopharmacol. 2020 Apr 6;251:112550.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9396666-01 48 Well
Hamster Microtubule-Associated Protein Tau Antibody (Anti-MAPT) ELISA Kit
Sign In for Pricing
View Details MBS9396666-02 96 Well
Hamster Microtubule-Associated Protein Tau Antibody (Anti-MAPT) ELISA Kit
Sign In for Pricing
View Details MBS9396666-03 5x 96 Well
Hamster Microtubule-Associated Protein Tau Antibody (Anti-MAPT) ELISA Kit
Sign In for Pricing
View Details MBS9396666-04 10x 96 Well
Hamster Microtubule-Associated Protein Tau Antibody (Anti-MAPT) ELISA Kit
Sign In for Pricing
View Details 
abx348544-01 50 µL
Cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3) Antibody (HRP)
Sign In for Pricing
View Details abx348544-02 100 µL
Cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3) Antibody (HRP)
Sign In for Pricing
View Details