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NBQX

Product Specifications

UNSPSC Description

NBQX (FG9202) is a highly selective and competitive AMPA receptor antagonist. NBQX has neuroprotective and anticonvulsant activity[1].

Target Antigen

iGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/NBQX.html

Solubility

1 M NaOH : 25 mg/mL (ultrasonic;warming;heat to 60°C)|DMSO : ≥ 75 mg/mL|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C(N1)C(NC2=C1C3=C(C([N+]([O-])=O)=C2)C(S(N)(=O)=O)=CC=C3)=O

Molecular Weight

336.28

References & Citations

[1]Fukushima K, et al. Characterization of Human Hippocampal Neural Stem/Progenitor Cells and Their Application to Physiologically Relevant Assays for Multiple Ionotropic Glutamate Receptors. J Biomol Screen. 2014 Sep; 19(8):1174-84.|[2]Wen Chen, et al. AMPA Receptor Antagonist NBQX Decreased Seizures by Normalization of Perineuronal Nets. PLoS One. 2016 Nov 23;11(11):e0166672.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-15068/NBQX-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-15068/NBQX-SDS-MedChemExpress.pdf

Clinical Information

Phase 1

CAS Number

118876-58-7

Available Sizes

Curated Selection

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