(Ala13) -Apelin-13 (TFA)
(Ala13) -Apelin-13 TFA is a potent apelin receptors (APJ) antagonist. (Ala13) -Apelin-13 TFA inhibits gastric motility through vagal cholinergic pathway[1].
Product Specifications
UNSPSC
12352209
Target
Apelin Receptor (APJ)
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ala13-apelin-13-tfa.html
Purity
98.78
Solubility
10 mM in DMSO
Smiles
NC(CC[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCCN)C(NCC(N2[C@@H](CCC2)C(N[C@@H](CCSC)C(N3[C@@H](CCC3)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C63H107N23O16S.xC2HF3O2
Molecular Weight
1474.73 (free acid)
References & Citations
[1]Bülbül M, et al. Apelin-13 inhibits gastric motility through vagal cholinergic pathway in rats. Am J Physiol Gastrointest Liver Physiol. 2018 Feb 1;314 (2) :G201-G210.|[2]O'Harte FPM, et al. Acylated apelin-13 amide analogues exhibit enzyme resistance and prolonged insulin releasing, glucose lowering and anorexic properties. Biochem Pharmacol. 2017 Dec 15;146:165-173.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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