Denosumab Antibody
Denosumab is a human monoclonal antibody administered via subcutaneous injection. It functions by binding to and inhibiting RANKL, thereby suppressing osteoclast formation and activity. This mechanism is utilized in research models of osteoporosis, bone metastasis, and rheumatoid arthritis to study bone resorption pathways.
Product Specifications
Product Name Alternative
Denosumab, Cancer, Inhibitor, inhibit, Immunoglobulin G 2, Immunoglobulin G2, Immunoglobulin G-2, Nuclear factor-κB, Nuclear factor-kappaB, NF-κB, Osteoporosis, Ranmark, RANKL, RANK
Target
Caspase, RANKL/RANK, Apoptosis, NF-κB
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Protein Biochemistry, Signal Transduction
Concentration
62.5 mg/mL
Purity
95.40% (May vary between batches)
Molecular Weight
144.71 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
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