Human CCL5 Protein

<strong>Human CCL5 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011849_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 14 kDa_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> EoCP protein, Eosinophil chemotactic cytokine protein, SIS delta protein, Small inducible cytokine A5 protein, T cell specific P228 protein, TCP228 protein, T cell specific RANTES protein, C C motif chemokine 5 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chen YC, Li KM, Zarivach R, Sun YJ, Sue SC. Human CCL5 trimer: expression, purification and initial crystallographic studies Acta Crystallogr F Struct Biol Commun. 2018 Feb 1;74(Pt 2):82-85._x000D_ 2: Persaud AT, Bennett SA, Thaya L, Burnie J, Guzzo C. Human monocytes store and secrete preformed CCL5, independent of de novo protein synthesis J Leukoc Biol. 2022 Mar;111(3):573-583._x000D_ 3: Dedoni S, Campbell LA, Harvey BK, Avdoshina V, Mocchetti I. The orphan G-protein-coupled receptor 75 signaling is activated by the chemokine CCL5 J Neurochem. 2018 Sep;146(5):526-539._x000D_ 4: Wang S, Xie F, Chu F, Zhang Z, Yang B, Dai T, Gao L, Wang L, Ling L, Jia J, van Dam H, Jin J, Zhang L, Zhou F. YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKKɛ-mediated phosphorylation Nat Immunol. 2017 Jul;18(7):733-743._x000D_ 5: Gangwani MR, Noel RJ Jr, Shah A, Rivera-Amill V, Kumar A. Human immunodeficiency virus type 1 viral protein R (Vpr) induces CCL5 expression in astrocytes via PI3K and MAPK signaling pathways J Neuroinflammation. 2013 Nov 13;10:136._x000D_ 6: Denisov SS, Ramírez-Escudero M, Heinzmann ACA, Ippel JH, Dawson PE, Koenen RR, Hackeng TM, Janssen BJC, Dijkgraaf I. Structural characterization of anti-CCL5 activity of the tick salivary protein evasin-4 J Biol Chem. 2020 Oct 16;295(42):14367-14378._x000D_ 7: Itoh A, Sadanari H, Takemoto M, Matsubara K, Daikoku T, Murayama T. Tricin inhibits the CCL5 induction required for efficient growth of human cytomegalovirus Microbiol Immunol. 2018 May;62(5):341-347._x000D_ 8: Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway Nat Immunol. 2003 May;4(5):491-6._x000D_ 9: Hoffmann A, Levchenko A, Scott ML, Baltimore D. The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation Science. 2002 Nov 8;298(5596):1241-5._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35524873">10: Ma Z, Zhang J, Wang L, Liu Y, Wang Y, Liu W, Xing G, Cheng K, Zheng W, Xiang L. Expression and purification of recombinant human CCL5 and its biological characterization Protein J. 2022 Apr;41(2):337-344. </a>_x000D_ _x000D_ <strong>Products Related to Human CCL5 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>