Ac-DEVD-CMK
Ac-DEVD-CMK (Caspase-3 Inhibitor III) is a selective and irreversible caspase-3 inhibitor. Ac-DEVD-CMK significantly inhibits apoptosis induced by high levels of glucose or Ingenol 3,20-dibenzoate?. Ac-DEVD-CMK can be used in a variety of experimental approaches to inhibit apoptosis[1][2][3].
Product Specifications
CAS Number
285570-60-7
Product Name Alternative
Caspase-3 Inhibitor III
UNSPSC
12352209
Target
Apoptosis; Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ac-devd-cmk.html
Purity
98.60
Solubility
10 mM in DMSO
Smiles
ClCC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O)=O)=O)=O
Molecular Formula
C21H31ClN4O11
Molecular Weight
550.94
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Caspase 3
Citation 01
Exp Neurol. 2024 Mar:373:114678.|J Agric Food Chem. 2025 Aug 27;73 (34) :21296-21308.|PLoS Pathog. 2024 Jul 22;20 (7) :e1012408.
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