Phospho-Ship2 (Tyr1135) Rabbit APC Conjugate

<strong> Phospho-Ship2 (Tyr1135) Rabbit APC Conjugate</strong>_x000D_ <strong>Catalog number:</strong> B2018907_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 138.60 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8℃_x000D_ <strong>Keywords:</strong> Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, Protein 51C, SH2 domain-containing inositol 5'-phosphatase 2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Artemenko Y, Gagnon A, Sorisky A. Catalytically inactive SHIP2 inhibits proliferation by attenuating PDGF signaling in 3T3-L1 preadipocytes J Cell Physiol. 2009 Jan;218(1):228-36._x000D_ 2: Fu CH, Lin RJ, Yu J, Chang WW, Liao GS, Chang WY, Tseng LM, Tsai YF, Yu JC, Yu AL. A novel oncogenic role of inositol phosphatase SHIP2 in ER-negative breast cancer stem cells: involvement of JNK/vimentin activation Stem Cells. 2014 Aug;32(8):2048-60._x000D_ 3: Elong Edimo W, Derua R, Janssens V, Nakamura T, Vanderwinden JM, Waelkens E, Erneux C. Evidence of SHIP2 Ser132 phosphorylation, its nuclear localization and stability Biochem J. 2011 Nov 1;439(3):391-401._x000D_ 4: Jesudason CD, Mason ER, Chu S, Oblak AL, Javens-Wolfe J, Moussaif M, Durst G, Hipskind P, Beck DE, Dong J, Amarasinghe O, Zhang ZY, Hamdani AK, Singhal K, Mesecar AD, Souza S, Jacobson M, Salvo JD, Soni DM, Kandasamy M, Masters AR, Quinney SK, Doolen S, Huhe H, Rizzo SJS, Lamb BT, Palkowitz AD, Richardson TI. SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late-onset Alzheimer's disease Alzheimers Dement (N Y). 2023 Nov 17;9(4):e12429._x000D_ 5: Zwaenepoel K, Goris J, Erneux C, Parker PJ, Janssens V. Protein phosphatase 2A PR130/B''alpha1 subunit binds to the SH2 domain-containing inositol polyphosphate 5-phosphatase 2 and prevents epidermal growth factor (EGF)-induced EGF receptor degradation sustaining EGF-mediated signaling FASEB J. 2010 Feb;24(2):538-47._x000D_ 6: Siddall HK, Warrell CE, Yellon DM, Mocanu MM. Ischemia-reperfusion injury and cardioprotection: investigating PTEN, the phosphatase that negatively regulates PI3K, using a congenital model of PTEN haploinsufficiency Basic Res Cardiol. 2008 Nov;103(6):560-8._x000D_ 7: Thomas MP, Erneux C, Potter BV. SHIP2: Structure, Function and Inhibition Chembiochem. 2017 Feb 1;18(3):233-247._x000D_ 8: Pedicone C, Meyer ST, Chisholm JD, Kerr WG. Targeting SHIP1 and SHIP2 in Cancer Cancers (Basel). 2021 Feb 20;13(4):890._x000D_ 9: Suwa A, Kurama T, Shimokawa T. SHIP2 and its involvement in various diseases Expert Opin Ther Targets. 2010 Jul;14(7):727-37._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32049315">10: Kerr WG, Pedicone C, Dormann S, Pacherille A, Chisholm JD. Small molecule targeting of SHIP1 and SHIP2 Biochem Soc Trans. 2020 Feb 28;48(1):291-300. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-Ship2 (Tyr1135) Rabbit APC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>