FLAC6

FLAC6 is a potent fluorinated detergent that can be used to solubilize membrane proteins (the native adenosine receptor A2AR, a G protein-coupled receptor, and two native transporters AcrB and BmrA) . FLAC6 can maintain the structural and functional integrity of different membrane proteins[1].

Product Specifications

CAS Number

2820046-26-0

UNSPSC

12352005

Target

Adenosine Receptor; Biochemical Assay Reagents

Type

Reference compound

Related Pathways

GPCR/G Protein; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/flac6.html

Smiles

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCNC([C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)O)O)CO)=O

Molecular Formula

C21H28F13NO11

Molecular Weight

717.43

References & Citations

[1]Faugier C, et al. Lactobionamide-based fluorinated detergent for functional and structural stabilization of membrane proteins. Methods. 2020 Aug 1;180:19-26.