RUC-1
RUC-1 (Compound 1) is an inhibitor for αIIbβ3 integrin. RUC-1 inhibits fibrin deposition and platelet aggregation in hybrid hαIIb/mβ3 receptors expressing mice. RUC-1 exhibits antithrombotic effect in hαIIb/mβ3 receptor expressing mice[1].
Product Specifications
CAS Number
796886-30-1
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ruc-1.html
Smiles
O=C1C=C(N2CCNCC2)N=C3SC(CC)=NN13
Molecular Formula
C11H15N5OS
Molecular Weight
265.33
References & Citations
[1]Blue R, et al., Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel alphaIIb-specific alphaIIbbeta3 antagonist. Blood. 2009 Jul 2;114 (1) :195-201.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1428972-01 0.02 mg (E-Coli)
Recombinant Yersinia pestis bv. Antiqua UDP-N-acetylmuramate--L-alanine ligase (murC)
Sign In for Pricing
View Details MBS1428972-02 0.02 mg (Yeast)
Recombinant Yersinia pestis bv. Antiqua UDP-N-acetylmuramate--L-alanine ligase (murC)
Sign In for Pricing
View Details MBS1428972-03 0.1 mg (E-Coli)
Recombinant Yersinia pestis bv. Antiqua UDP-N-acetylmuramate--L-alanine ligase (murC)
Sign In for Pricing
View Details MBS1428972-04 0.1 mg (Yeast)
Recombinant Yersinia pestis bv. Antiqua UDP-N-acetylmuramate--L-alanine ligase (murC)
Sign In for Pricing
View Details MBS1428972-05 0.02 mg (Baculovirus)
Recombinant Yersinia pestis bv. Antiqua UDP-N-acetylmuramate--L-alanine ligase (murC)
Sign In for Pricing
View Details MBS1428972-06 0.02 mg (Mammalian-Cell)
Recombinant Yersinia pestis bv. Antiqua UDP-N-acetylmuramate--L-alanine ligase (murC)
Sign In for Pricing
View Details