Chlorin e6 (trisodium)

Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll, belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm. Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation, enabling real-time identification of tumor boundaries and progression. Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions[1][2][3].

Product Specifications

CAS Number

[72984-36-2]

Product Name Alternative

Ce6 (trisodium)

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Photosensitizer

Type

Biochemical Assay Reagents

Related Pathways

Apoptosis

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/chlorin-e6-trisodium.html

Purity

98.74

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5 mg/mL (ultrasonic)

Smiles

O=C(O[Na])C/C1=C2[C@H]([C@@H](C(/C=C3N/C(C(C=C)=C\3C)=C\C4=N/C(C(CC)=C4C)=C\C5=C(C)C(C(O[Na])=O)=C1N5)=N\2)C)CCC(O[Na])=O

Molecular Formula

C34H33N4Na3O6

Molecular Weight

662.62

Precautions

H302, H315, H319, H335

References & Citations

[1]Chin WW, et al. The potential application of chlorin e6-polyvinylpyrrolidone formulation in photodynamic therapy. Photochem Photobiol Sci. 2006 Nov;5 (11) :1031-7. |[2]Chin WW, et al. Fluorescence imaging and phototoxicity effects of new formulation of chlorin e6-polyvinylpyrrolidone. J Photochem Photobiol B. 2006 Aug 1;84 (2) :103-10.|[3]Rybkin AY, et al. Nanoparticles of N-Vinylpyrrolidone Amphiphilic Copolymers and Pheophorbide a as Promising Photosensitizers for Photodynamic Therapy: Design, Properties and In Vitro Phototoxic Activity. Pharmaceutics. 2023 Jan 12;15 (1) :273.