Biotinylated Human STEAP1 Full Length Protein, Avitag™, Flag&His Tag (Detergent)

Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron (III) . Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.

Product Specifications

Background

Specifications

This protein carries a Flag tag at the N-terminus, and a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 44.7 kDa. The protein migrates as 40-43 kDa and 65-70 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q9UHE8-1

Expression Region

Glu 2 - Leu 339

Host

HEK293

Target

STEAP1

Conjugation

Biotin-labeled

Tag

N-Flag & C-10xHis & C-Avi

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Biotinylated Human STEAP1 Full Length Protein, Avitag,Flag&His Tag (Cat. No. ST1-H82D3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-STEAP1 Antibody with a linear range of 0.002-0.156 μg/mL (QC tested).

Format

Liquid

Buffer

50 mM HEPES, 150 mM NaCl, Buffer A, pH7.5

Additives

Glycerol

Molecular Weight

44.7 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C, avoid light

Package Size

20ug*1

Host or Source

HEK293

Species

Human

Protein ID

Q9UHE8-1

Preservative

Glycerol

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