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[D-Trp2,7,9] Substance P

Product Specifications

UNSPSC Description

[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively[1].

Target Antigen

Neurokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/d-trp2-7-9-substance-p.html

Solubility

10 mM in DMSO

Smiles

CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CNC2=CC=CC=C12)NC([C@H](CC3=CC=CC=C3)NC([C@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H]4N(CCC4)C([C@H](CCCCN)NC([C@H](NC([C@@H](N)CCCNC(N)=N)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)CC7=CNC8=CC=CC=C78)=O)=O)=O)=O

Molecular Weight

1604.92

References & Citations

[1]S H Buck, et al. Agonist and antagonist binding to tachykinin peptide NK-2 receptors. Life Sci. 1988;42(26):2701-8.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P3802/D-Trp2-7-9-Substance-P-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P3802/

Clinical Information

No Development Reported

CAS Number

100930-11-8

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