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Evolocumab Antibody

Evolocumab is a human monoclonal antibody that inhibits PCSK9, preventing its interaction with the LDL receptor. It is widely used in preclinical and clinical research for studying hypercholesterolemia and atherosclerotic cardiovascular disease, including in vitro binding assays and in vivo models of lipid metabolism.

Product Specifications

Product Name Alternative

AMG 145, AMG145, AMG-145, atherosclerotic cardiovascular disease, Evolocumab, hypercholesterolemia, Inhibitor, LDLR, PCSK9, inhibit, Serine endopeptidases, Ser/Thr Protease, Serine proteases, Threonine proteases, Repatha

Target

NF-κB, TLR, Serine Protease, LDLR, Others

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction

Concentration

140 mg/mL

Purity

95.00% (May vary between batches)

Molecular Weight

141.8 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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