Evolocumab Antibody
Evolocumab is a human monoclonal antibody that inhibits PCSK9, preventing its interaction with the LDL receptor. It is widely used in preclinical and clinical research for studying hypercholesterolemia and atherosclerotic cardiovascular disease, including in vitro binding assays and in vivo models of lipid metabolism.
Product Specifications
Product Name Alternative
AMG 145, AMG145, AMG-145, atherosclerotic cardiovascular disease, Evolocumab, hypercholesterolemia, Inhibitor, LDLR, PCSK9, inhibit, Serine endopeptidases, Ser/Thr Protease, Serine proteases, Threonine proteases, Repatha
Target
NF-κB, TLR, Serine Protease, LDLR, Others
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction
Concentration
140 mg/mL
Purity
95.00% (May vary between batches)
Molecular Weight
141.8 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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