Caspase 9 Chromogenic Substrate

<strong>Caspase 9 Chromogenic Substrate</strong>_x000D_ <strong>Catalog number:</strong> B2011100_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 674.7 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various chemical, biochemical and immunological applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> pNA_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Araya LE, Soni IV, Hardy JA, Julien O. Deorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling ACS Chem Biol. 2021 Nov 19;16(11):2280-2296._x000D_ 2: Molnár T, Pallagi P, Tél B, Király R, Csoma E, Jenei V, Varga Z, Gogolák P, Odile Hueber A, Máté Z, Erdélyi F, Szabó G, Pettkó-Szandtner A, Bácsi A, Virág L, Maléth J, Koncz G. Caspase-9 acts as a regulator of necroptotic cell death FEBS J. 2021 Nov;288(22):6476-6491._x000D_ 3: Chehade H, Fox A, Mor GG, Alvero AB. Determination of Caspase Activation by Western Blot Methods Mol Biol. 2021;2255:1-12._x000D_ 4: Soni IV, Hardy JA. Caspase-9 Activation of Procaspase-3 but Not Procaspase-6 Is Based on the Local Context of Cleavage Site Motifs and on Sequence Biochemistry. 2021 Sep 21;60(37):2824-2835._x000D_ 5: Huber KL, Serrano BP, Hardy JA. Caspase-9 CARD : core domain interactions require a properly formed active site Biochem J. 2018 Mar 29;475(6):1177-1196._x000D_ 6: Serrano BP, Hardy JA. Phosphorylation by protein kinase A disassembles the caspase-9 core Cell Death Differ. 2018 Jun;25(6):1025-1039._x000D_ 7: Han J, Goldstein LA, Hou W, Watkins SC, Rabinowich H. Involvement of CASP9 (caspase 9) in IGF2R/CI-MPR endosomal transport Autophagy. 2021 Jun;17(6):1393-1409._x000D_ 8: Long HZ, Cheng Y, Zhou ZW, Luo HY, Wen DD, Gao LC. PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer's Disease and Parkinson's Disease Front Pharmacol. 2021 Apr 15;12:648636._x000D_ 9: Serrano BP, Szydlo HS, Alfandari D, Hardy JA. Active site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9 J Biol Chem. 2017 Dec 29;292(52):21352-21365._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25031754">10: Sangawa A, Shintani M, Yamao N, Kamoshida S. Phosphorylation status of Akt and caspase-9 in gastric and colorectal carcinomas Int J Clin Exp Pathol. 2014 May 15;7(6):3312-7. eCollection 2014.</a>_x000D_ _x000D_ <strong>Products Related to Caspase 9 Chromogenic Substrate can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>