ACP1b

ACP1b is an activator for ClpP protease with Kd of 3.2 μM, and exhibits antibacterial activity. ACP1b inhibits N. meningitidis and H. influenzae with MBC of 16 and 8 μg/mL[1].

Product Specifications

CAS Number

1371635-84-5

UNSPSC

12352005

Target

Bacterial; ClpP

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/acp1b.html

Smiles

CC(C)(C(NCCSC1=CC=CC=C1Cl)=O)S(=O)(C2=NC=C(C=C2)C(F)(F)F)=O

Molecular Formula

C18H18ClF3N2O3S2

Molecular Weight

466.93

References & Citations

[1]Leung E, et al., Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease. Chem Biol. 2011 Sep 23;18 (9) :1167-78.