ACP1b
ACP1b is an activator for ClpP protease with Kd of 3.2 μM, and exhibits antibacterial activity. ACP1b inhibits N. meningitidis and H. influenzae with MBC of 16 and 8 μg/mL[1].
Product Specifications
CAS Number
1371635-84-5
UNSPSC
12352005
Target
Bacterial; ClpP
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/acp1b.html
Smiles
CC(C)(C(NCCSC1=CC=CC=C1Cl)=O)S(=O)(C2=NC=C(C=C2)C(F)(F)F)=O
Molecular Formula
C18H18ClF3N2O3S2
Molecular Weight
466.93
References & Citations
[1]Leung E, et al., Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease. Chem Biol. 2011 Sep 23;18 (9) :1167-78.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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