Ilexsaponin A

Ilexsaponin A, isolated from the root of Ilex pubescens, attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. Ilexsaponin A can reduce myocardial infarct size, lower the serum levels of LDH, AST and CK-MB, increase cellular viability and inhibit apoptosis in hypoxia/reoxygenation cardiomyocytes[1].

Product Specifications

CAS Number

[108524-93-2]

UNSPSC

12352005

Hazard Statement

H302

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ilexsaponin-a.html

Purity

99.53

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC[C@H]([C@@H](O)[C@H](O)[C@H]1O)O[C@H]1OC([C@]23[C@]([C@](O)([C@H](C)CC3)C)([H])C4=CC[C@@]([C@@]5([C@@]([C@](C)([C@@H](O)CC5)C(O)=O)([H])CC6)C)([H])[C@]6(C)[C@]4(C)CC2)=O

Molecular Formula

C36H56O11

Molecular Weight

664.82

Precautions

H302

References & Citations

[1]Zhang SW, et al. Ilexsaponin A attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. PLoS One. 2017 Feb 9;12 (2) :e0170984.