Protoescigenin 21-tiglate
Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively[1].
Product Specifications
CAS Number
7047-43-0
Product Name Alternative
(E) -21-Angeloyl-protoaescigenin
UNSPSC
12352211
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
CANCER
Assay Protocol
https://www.medchemexpress.com/protoescigenin-21-tiglate.html
Smiles
OC[C@]12[C@](CC(C)([C@H]([C@@H]2O)OC(/C(C)=C/C)=O)C)([H])C3=CC[C@@]([C@@]4([C@@]([C@](C)([C@H](CC4)O)CO)([H])CC5)C)([H])[C@]5(C)[C@@]3(C[C@H]1O)C
Molecular Formula
C35H56O7
Molecular Weight
588.81
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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