Protoescigenin 21-tiglate
Product Specifications
UNSPSC Description
Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively[1].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
CANCER
Assay Protocol
https://www.medchemexpress.com/protoescigenin-21-tiglate.html
Smiles
OC[C@]12[C@](CC(C)([C@H]([C@@H]2O)OC(/C(C)=C/C)=O)C)([H])C3=CC[C@@]([C@@]4([C@@]([C@](C)([C@H](CC4)O)CO)([H])CC5)C)([H])[C@]5(C)[C@@]3(C[C@H]1O)C
Molecular Weight
588.81
References & Citations
[1]Yang Y, et al. 16-Tigloyl linked barrigenol-like triterpenoid from Semen Aesculi and its anti-tumor activity in vivo and in vitro[J]. RSC advances, 2019, 9(54): 31758-31772.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N13115A/Protoescigenin-21-tiglate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N13115A/
Clinical Information
No Development Reported
CAS Number
7047-43-0
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