Ribonuclease H (RNase H)

<strong>Ribonuclease H (RNase H)</strong>_x000D_ <strong>Catalog number:</strong> B2016638_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 units_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> rnase h_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong> _x000D_ 1: Chan SH, Whipple JM, Dai N, Kelley TM, Withers K, Tzertzinis G, Corrêa IR Jr, Robb GB. RNase H-based analysis of synthetic mRNA 5' cap incorporation RNA. 2022 Aug;28(8):1144-1155. _x000D_ 2: Kanaya S. Ribonuclease H FEBS J. 2009 Mar;276(6):1481. _x000D_ 3: Hyjek M, Figiel M, Nowotny M. RNases H: Structure and mechanism DNA Repair (Amst). 2019 Dec;84:102672. _x000D_ 4: Beverly M, Dell A, Parmar P, Houghton L. Label-free analysis of mRNA capping efficiency using RNase H probes and LC-MS Anal Bioanal Chem. 2016 Jul;408(18):5021-30. _x000D_ 5: Ilina TV, Brosenitsch T, Sluis-Cremer N, Ishima R. Retroviral RNase H: Structure, mechanism, and inhibition Enzymes. 2021;50:227-247. _x000D_ 6: Cerritelli SM, Crouch RJ. Ribonuclease H: the enzymes in eukaryotes FEBS J. 2009 Mar;276(6):1494-505. _x000D_ 7: Moelling K. Targeting the retroviral ribonuclease H by rational drug design AIDS. 2012 Oct 23;26(16):1983-93. _x000D_ 8: Heuzé J, Kemiha S, Barthe A, Vilarrubias AT, Aouadi E, Aiello U, Libri D, Lin YL, Lengronne A, Poli J, Pasero P. RNase H2 degrades toxic RNA:DNA hybrids behind stalled forks to promote replication restart EMBO J. 2023 Dec 1;42(23):e113104. _x000D_ 9: Schultz SJ, Champoux JJ. RNase H activity: structure, specificity, and function in reverse transcription Virus Res. 2008 Jun;134(1-2):86-103. _x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31894217">10: Wang Y , Hu N , Liu C , Nie C , He M , Zhang J , Yu Q , Zhao C , Chen T , Chu X . An RNase H-powered DNA walking machine for sensitive detection of RNase H and the screening of related inhibitors Nanoscale. 2020 Jan 23;12(3):1673-1679. </a>_x000D_ <br><strong>Products Related to Ribonuclease H (RNase H) can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>