Rhodanine

Rhodanine is a selective Echovirus 12 proliferation inhibitor and intermediate. Rhodanine is used to determine tannase activity. Rhodanine can be used in the synthesis of anticancer and antibacterial agents[1][2][3][4][5].

Product Specifications

CAS Number

[141-84-4]

UNSPSC

12352200

Hazard Statement

H302, H319

Target

Biochemical Assay Reagents; Drug Intermediate; Enterovirus

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection; Others

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/rhodanine.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC(SC1)=S

Molecular Formula

C3H3NOS2

Molecular Weight

133.20

Precautions

H302, H319

References & Citations

[1]Sing WT, et al. Arylalkylidene rhodanine with bulky and hydrophobic functional group as selective HCV NS3 protease inhibitor. Bioorg Med Chem Lett. 2001 Jan 22;11 (2) :91-4.|[2]Enemuor S C, et al. Culture conditions for the production of a tannase of Aspergillus tamarii IMI388810 (B) . African Journal of Biotechnology, 2009, 8 (11) . |[3]Eggers HJ, et al. Rhodanine: a selective inhibitor of the multiplication of echovirus 12. Science. 1970 Jan 16;167 (3916) :294-7.|[4]AbdelKhalek A, et al. In Vitro Antibacterial Activity of Rhodanine Derivatives against Pathogenic Clinical Isolates. PLoS One. 2016 Oct 6;11 (10) :e0164227.|[5]Gao J, et al. Fluorescent ferroptosis inducers leveraging the pharmacological activity of rhodanine to promote antitumor immunity. Science China Chemistry, 2025: 1-14.