Anti-IL-4 [SB240683 (Pascolizumab, humanized 3B9)], Rabbit IgG, kappa
Product Specifications
Gene Name
[IL-4]
NCBI Gene ID
3565
Reactivity
Human, cynomolgus monkeys
Storage Conditions
Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.
Specificity
This antibody binds human and cynomolgus monkey IL-4 and does not cross react with IL-4 from mouse, rat, cow, goat or horse. It does show binding to glycosylated interleukin-4. Interleukin-4 is a receptor for both interleukin 4 and interleukin 13. It couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Other Gene Names
[IL4; IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1; IL-4; BSF-1]
Short Name
[IL-4]
Other Product Names
[interleukin-4 isoform 1; Interleukin-4; interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1; interleukin 4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra]
NCBI GI Number
4504669
NCBI Accession Number
NP_000580.1
NCBI GB Accession Number
NM_000589.3
Uniprot Accession Number
P05112
Available Sizes
Curated Selection
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