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JMV 236

JMV 236 is a cholecystokinin antagonist with appetite-suppressing activity. JMV 236 affects the regulation of food intake through the interaction of the intestinal endogenous peptide PrRP and the CCK1 receptor. The administration of JMV 236 activates PrRP neurons located in the NTS, thereby enhancing its appetite-suppressing effect. JMV 236 has significant effects on areas of the central nervous system associated with food intake, especially during states of starvation[1].

Product Specifications

CAS Number

113137-57-8

UNSPSC

12352209

Target

Histone Methyltransferase

Type

Peptides

Related Pathways

Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/jmv-236.html

Smiles

NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCCC)NC([C@@H](NC(CNC([C@H](CCCC)NC([C@@H](NC([C@H](CC(O)=O)NC(OC(C)(C)C)=O)=O)CC2=CC=C(C=C2)OS(=O)(O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O

Molecular Formula

C56H74N10O18S

Molecular Weight

1207.31

References & Citations

[1]Cholecystokinin system is involved in the anorexigenic effect of peripherally applied palmitoylated prolactin-releasing peptide in fasted mice

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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