Anti-CD45RC [OX-22], Rabbit IgG, kappa

Product Specifications

Gene Name

[CD45RC]

NCBI Gene ID

24699

Reactivity

Rat

Storage Conditions

Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.

Specificity

OX-22 binds specifically to the high molecular weight form of the leucocyte common antigen, CD45RC. OX-22 and OX-31 compete for binding but do not compete with OX-32. The antigen is expresssed on the surface of B cells, around half of bone marrow cells, all CD8+ve T cells, and is able to differentiate between CD4+CD45RChigh (Th1-like) and CD4+CD45RClow (Th2-like) cell types. CD45 extracellular domain is able to interact with a number of different proteins including CD4, TCR, CD2, Thy-1 and CD26. CD45 is important for signalling throguh the T cell receptor and in the selection of T and B lymphocytes.

Other Gene Names

[Ptprc; Ptprc; Lca; RT7; CD45; L-CA; T200; L-CA]

Short Name

[CD45RC]

Other Product Names

[receptor-type tyrosine-protein phosphatase C isoform 3; Receptor-type tyrosine-protein phosphatase C; receptor-type tyrosine-protein phosphatase C; Protein tyrosine phosphatase, receptor-type, c polypeptide; T200 glycoprotein; leucocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; protein tyrosine phosphatase, receptor type, C; Leukocyte common antigen; L-CA; T200; CD_antigen: CD45]