Anti-Terminal Deoxynucleotidyl Transferase [32D5]

The antibody is specific for TdT. TdT catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

[DNA nucleotidylexotransferase isoform 2; DNA nucleotidylexotransferase; DNA nucleotidylexotransferase; terminal transferase; terminal addition enzyme; terminal deoxynucleotidyltransferase; deoxynucleotidyltransferase, terminal; terminal deoxyribonucleotidyltransferase; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; DNA nucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase]