Anti-Glypican 3 [15G1]
Product Specifications
NCBI Gene ID
2719
Reactivity
Human, Cynomolgus Monkey, Rat
Storage Conditions
Store at 4 °C for up to 3 months. For longer storage, aliquot and store at -20 °C.
Specificity
This antibody binds an epitope between amino acids 420 to 470 of the human glypican 3 (GPC3). This antibody cross reacts with cynomolgus monkey and rat GPC3. Glypican-3 is an oncofetal antigen that belongs to the glypican family of glycosyl-phosphatidylinositol-anchored heparin sulfate proteoglycans. It negatively regulates the hedgehog signaling pathway and positively regulates the canonical Wnt signaling pathway. Multiple studies have revealed that GPC-3 is overexpressed in hepatocellular carcinoma (HCC).
Other Gene Names
[GPC3; GPC3; SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; OCI5]
Short Name
[Glypican 3]
Other Product Names
[glypican-3 isoform 4; Glypican-3; glypican-3; secreted glypican-3; glypican proteoglycan 3; intestinal protein OCI-5; heparan sulphate proteoglycan; glypican 3; GTR2-2; Intestinal protein OCI-5; MXR7]
NCBI GI Number
257471010
NCBI Accession Number
NP_001158091.1
NCBI GB Accession Number
NM_001164619.1
Uniprot Accession Number
P51654
Available Sizes
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