(15α) -15,26-Dihydroxylanosta-7,9 (11),24-trien-3-one
(15α) -15,26-Dihydroxylanosta-7,9 (11),24-trien-3-one shows a 5a-reductase inhibitory activity with an IC50 value of 41.9 μM. (15α) -15,26-Dihydroxylanosta-7,9 (11),24-trien-3-one inhibits the growth of the ventral prostate induced by testosterone in rat. (15α) -15,26-Dihydroxylanosta-7,9 (11),24-trien-3-one is promising for research of benign prostatic hyperplasia (BPH) as well as other 5α-dihydrotestosterone (DHT) -related disorders, such as acne and male pattern baldness[1].
Product Specifications
CAS Number
420781-85-7
UNSPSC
12352211
Target
5 alpha Reductase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/15α-15-26-dihydroxylanosta-7-9-11-24-trien-3-one.html
Smiles
C[C@]12C3=CC[C@](C(C)(C(CC4)=O)C)([H])[C@@]4(C)C3=CC[C@@]1([C@@](C[C@@H]2O)([H])[C@H](C)CC/C=C(C)/CO)C
Molecular Formula
C30H46O3
Molecular Weight
454.68
References & Citations
[1]Liu J, et al. 5alpha-reductase inhibitory effect of triterpenoids isolated from Ganoderma lucidum. Biol Pharm Bull. 2006 Feb;29 (2) :392-5.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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