Anti-BCMA [CA8]

Product Specifications

Gene Name

[BCMA]

NCBI Gene ID

1062

Reactivity

Human, Cynomolgus Monkey

Storage Conditions

Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Specificity

This antibody binds human and cynomolgus monkey BCMA and does not bind TACI or BAFF-R proteins. BCMA acts as a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. BCMA expression is highest on terminally differentiated B cells. BCMA is involved in mediating the survival of plasma cells for maintaining long-term humoral immunity. It also activates NF-kappa-B and JNK. The expression of BCMA has been linked to a number of cancers, autoimmune disorders, and infectious diseases.

Other Gene Names

[CENPE; CENPE; KIF10; CENP-E; PPP1R61; CENP-E]

Short Name

[BCMA]

Other Product Names

[centromere-associated protein E; Centromere-associated protein E; centromere-associated protein E; kinesin family member 10; kinesin-related protein CENPE; Centromere autoantigen E (312kD); protein phosphatase 1, regulatory subunit 61; centromere protein E, 312kDa; Centromere protein E; CENP-E; Kinesin-related protein CENPE]