Anti-BCMA [CA8]
Product Specifications
Gene Name
[BCMA]
NCBI Gene ID
1062
Reactivity
Human, Cynomolgus Monkey
Storage Conditions
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Specificity
This antibody binds human and cynomolgus monkey BCMA and does not bind TACI or BAFF-R proteins. BCMA acts as a receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. BCMA expression is highest on terminally differentiated B cells. BCMA is involved in mediating the survival of plasma cells for maintaining long-term humoral immunity. It also activates NF-kappa-B and JNK. The expression of BCMA has been linked to a number of cancers, autoimmune disorders, and infectious diseases.
Other Gene Names
[CENPE; CENPE; KIF10; CENP-E; PPP1R61; CENP-E]
Short Name
[BCMA]
Other Product Names
[centromere-associated protein E; Centromere-associated protein E; centromere-associated protein E; kinesin family member 10; kinesin-related protein CENPE; Centromere autoantigen E (312kD); protein phosphatase 1, regulatory subunit 61; centromere protein E, 312kDa; Centromere protein E; CENP-E; Kinesin-related protein CENPE]
NCBI GI Number
71061468
NCBI Accession Number
NP_001804.2
NCBI GB Accession Number
NM_001813.2
Uniprot Accession Number
Q02224
Available Sizes
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